A man of endless curiosity

first_img“I had trouble deciding what to do,” says postdoctoral fellow Emre Basar, sitting at a bench in Professor Judy Lieberman’s lab in Harvard Medical School’s Immune Disease Institute. Small wonder. Basar, who already obtained an M.D. and is now pursuing a Ph.D., acknowledges that he has been “interested in a lot of things, particularly medicine, engineering, and business.”Born in Istanbul and educated at a French-bilingual school in Germany, Basar is fluent in German, French, English, and Turkish, and reads and writes Latin. Now he is seeking to understand how small interfering RNAs (siRNAs) can be harnessed as a drug against HIV and breast cancer. His global-minded, integrative approach to science, and life, is helping to build connections in research at Harvard and beyond.Basar earned his M.D. from the Ruhr-University Bochum in Germany, finally deciding on medicine, he says, because it encompasses such a broad range of knowledge. “Medicine starts with biochemistry and physiology, but also includes clinical and practical components,” he says. “Not only do you have to know the pathobiology, you also have to interpret MR (magnetic resonance) images, know how to stitch the skin, and understand how to talk to a patient. Medicine has such a broad range of interactions and knowledge fields,” he says.Basar’s decision to attend medical school was also strongly influenced by his father, a professor of civil engineering and computational mechanics who died in 2002. “My father was an outstanding scientist and teacher, who truly cared about people and used his education to better the lives of others,” Basar says. For Basar, a natural networker with a love for travel, medicine offered the opportunity to explore new worlds, both intellectually and physically, while following in his father’s footsteps by helping others.Basar began his studies at Ruhr-University Bochum with a full stipend awarded by the German National Academic Foundation, which aims to build an interdisciplinary and international outlook among scholarship recipients.During medical school, Basar had a number of clinical rotations and fellowships throughout the world. One of the most influential was a practical in a private hospital in Istanbul. “My first real insight into clinical experience was early on in my medical studies: I was working at the German Hospital in Istanbul when the city was hit by a huge earthquake. I think there were 20,000 people killed. And due to the chaos caused by the earthquake, I had to help,” says Basar. “I had the chance not only to assist, but to perform some surgery myself, which was exceptional after only one year at medical school.”Basar was surprised by how much he enjoyed working in a clinical environment. “At the beginning of my medical studies I thought I would be more interested in biology or biochemistry. I didn’t think that I would like the clinical aspects as much, in particular the operations and having contact with patients,” he says. “But interestingly, I ended up enjoying this part the most.”In addition to his time abroad in Turkey, Basar attended a training fellowship at Imperial College in London, had a medical clerkship at the Hochgebirgsklinik in Davos, Switzerland, and completed an internship in the Neurointensive Care Unit at Massachusetts General Hospital in Boston.Basar enjoyed living in Boston so much that he returned to the city after completing his M.D. “I wanted to do biomedical research, and I knew that I would come back to Harvard to combine graduate studies with a postdoc. It had to be Harvard because the access to hospitals and the biotechnology industry surrounding Boston, you can’t beat,” Basar says. “Also, Boston is a very international city and I like that.”In May 2005, Basar started a research fellowship at Brigham and Women’s Hospital (BWH), working to optimize an existing vaccine against anthrax. Although the vaccine component he tested proved to be inferior to the existing vaccine, Basar views the time as important to his career because he learned research techniques vital to biochemistry and immunology.“I became more familiar with what research is,” Basar says. “During medical school, my focus was on surgery, so my research fellowship at the Brigham helped me develop research techniques and get a sense of what’s important in science and the emerging trends in the field,” he says. “It was during my time at BWH that I became very interested in RNA interference [RNAi] and its applications in translational research.”Basar compares the current scientific interest in RNAi to the excitement caused by gene therapy two decades ago. “Craig Mello and Andrew Fire got the Nobel Prize for unveiling the mechanism of RNA interference, only eight years after their discovery. Normally, it takes decades to get a Nobel Prize; however, RNAi is an incredibly important technique: barely a decade after its discovery it has already revolutionized biomedical research.” Basar says.According to Basar, both gene therapy and RNAi can be harnessed to regulate gene expression. While gene therapy targets the DNA in the nucleus of the cell, “RNAi affects the cell only at the messenger RNA level, which is more elegant and safer as the cell’s genomic information remains untouched,” he says.Basar explains that genes are encoded in DNA and are then transcribed into messenger RNAs, which are in turn translated into proteins. Because proteins play a pivotal role in the regulation of all kinds of cellular processes, defects in their function or regulation can lead to disease. “In the case of AIDS, for instance, it is the immune cell receptors CD4 and CCR5 that are critical for HIV transmission,” Basar says. He explains that both CD4 and CCR5 are proteins that mediate binding of the virus to the cell membrane and hence enable HIV to penetrate and infect immune cells.According to Basar, one way to induce RNAi is by introducing small interfering RNAs (siRNAs) into a cell. Once delivered into the cytoplasm of the target cell, siRNAs bind to their complementary messenger RNA and when this happens the messenger RNA is cleaved and destroyed, he says. “If you transfect cells with siRNAs targeting the CCR5 co-receptor, RNAi will dramatically downregulate the expression of this receptor,” he says, and as a result, HIV will not find any binding site on the cell membrane to enter the cell. “When you knock out the CCR5 receptor, the door for HIV to enter its target cell is closed,” Basar says.During his work at BWH, Basar became very interested in harnessing RNAi to fight AIDS and cancer. “I started to look for a lab that combined RNAi with HIV or cancer research,” Basar says. Later that year, at an HIV symposium, Basar met Lieberman, a senior investigator at the Immune Disease Institute at Harvard Medical School, and was intrigued by her research. Lieberman’s lab was studying ways that RNAi could be used to create drugs for the prevention or treatment of viral infections, like HIV, and cancer. In fact, Lieberman’s group was the first one to successfully use siRNAs to inhibit genital herpes simplex virus transmission in mice.Basar joined Lieberman’s team in 2006 and his first research project was focused on the development of an siRNA-based topical microbicide to prevent vaginal HIV transmission in mice. As a result of this research, Basar and his colleagues have developed two promising strategies based on RNAi technology and plan to publish their findings soon.Basar is now applying the knowledge he gained working on an siRNA-based HIV microbicide toward developing new methods of siRNA delivery into breast cancer stem cells. At the same time he has become more and more interested in understanding how siRNAs are trafficked within a cell.Although RNA interference offers an exciting new approach for drug development, one major obstacle for using siRNAs as therapy remains their delivery into target cells, says Basar. “The big question, in the context of RNAi, is: How can you deliver siRNAs into different target cells? And how can you ensure that siRNAs, upon uptake into cells, translocate into the cytoplasm to become functional?”Basar thinks that this mechanistic question will occupy him and other researchers well into the future. “How are siRNAs binding to a cell, how are they taken up into a cell, and what’s their fate once inside the cell? There are so many questions,” he says. “A few years ago, I couldn’t understand how a scientist could spend a decade focusing on understanding a biological mechanism, because as a physician my focus has always been translational research,” he says. “Now, I’ve become the scientist interested in the mechanisms of siRNA trafficking.”Basar says that the biological processes underlying HIV and cancer are far more complex than he initially imagined. “That’s why you have to combine the knowledge of many researchers to get the most out of science.” Basar believes that building bridges and improving communication between scientists is just as important as the research itself.“Science has a bad reputation for not reaching out, for not networking and getting outside the lab,” Basar says. “Nowadays biomedical research requires a high degree of specialization, which is very costly, so it’s important to team up with other people to share knowledge and take advantage of the special skills research fellows have developed over years,” he says.In an effort to build social bridges across Harvard, Basar served as co-chair of the Harvard Medical School Postdoctoral Association for two years, where he coordinated a series of networking events. He also joined with fellow German students in 2008 to organize the first Harvard German Conference, which featured Frank-Walter Steinmeier, the German secretary of state, as the keynote speaker.Basar has also expanded his networking efforts outside the lab by becoming a partner of the start-up company InterNations, the first online international community geared toward connecting expatriates and other globally minded people. Basar regularly helps organize InterNations events in Boston. “Building an international network and getting people together inspired me; it’s a very intriguing concept,” he says.But using science to help others remains Basar’s core inspiration. “For me as a physician it’s exciting to work on a drug, to work on something that immediately translates into healing a disease,” Basar says. “There’s a possibility that our research and contributions will help fight disease and hopefully positively impact health. That’s the power of research.”last_img read more

New Cassel Man Sentenced for Murder

first_imgSign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York A man was sentenced Thursday to 35 years to life in prison for shooting a 31-year-old man to death after the gunman and victim got into an argument in their hometown of New Cassel two years ago.A Nassau County jury had found Naqunne Jackson guilty in December of second-degree murder and criminal possession of a weapon following a week-long trial.“This sentence will ensure that this defendant will be held accountable for taking the life of a young man and will not be a threat to the public for a very long time,” Acting Nassau County District Attorney Madeline Singas said.Prosecutors said Jackson shot William Moody two times after an argument on Prospect Avenue at 3:30 p.m. on Sept. 22, 2013.Moody was later found dead from his injuries near the scene of the shooting on State Street. Nassau County police arrested Jackson three days later.last_img read more

Premiership: West Ham Halts Terrible Run at Everton

first_imgWest Ham yesterday halted their disastrous start to the season with a first Premier League win under Manuel Pellegrini as they outplayed Everton in a lively contest at Goodison Park.Andriy Yarmolenko’s first Hammers goal opened the scoring, the Ukrainian finishing off a slick counter that went from the halfway line to the net in three passes, Marko Arnautovic with the assist.Yarmolenko got his second in the 31st minute with a fine curled effort from just inside the box after a Jordan Pickford error gave possession to Mark Noble. Just before the break, Gylfi Sigurdsson powered in a header from Jonjoe Kenny’s cross, converting after Cenk Tosun missed two good chances.West Ham were coming in on the back of four consecutive defeats – a fifth straight loss would have constituted their worst ever opening of a league campaign.But Arnautovic ensured that run came to an end when he struck clinically after a one-two with Pedro Obiang, the Hammers again profiting on the break despite Everton’s spirited start to the second half.The Toffees were unbeaten under new manager Marco Silva before Sunday’s match, but had only won once, and they will regret the handful of individual errors and missed chances that was ultimately the difference between the two sides.Even in the game’s latter stages they were pouring forward but could still not find the net, substitute Oumar Niasse rattling the crossbar from close range after Lucas Digne’s cross.Victory lifts the Hammers up to 16th, with Burnley taking their place at the bottom of the table after losing 1-0 at Wolves earlier in the day. Everton are now 10th, with six points from their first five games.West Ham were booed off after their previous game, a 1-0 home defeat by Wolves. Ex-England captain Alan Shearer described that showing as “embarrassing, hopeless and pathetic”.This was a performance much closer to what fans will have been expecting since a summer spend of £100m and the arrival of ex-Real Madrid manager Pellegrini, title winner with Manchester City in 2014.They were far better organised at the back, more confident in possession, and played with real energy against a full-blooded Everton side who were just determined to attack.Lukas Fabianksi’s goal withstood seven first-half attempts before Sigurdsson’s unstoppable bullet header, and on the break Felipe Anderson was exceptional in his link-up play with Yarmolenko and Arnautovic, who was forced off in the second half.Pellegrini said before this fixture he “trusts now more than ever” his ability to achieve at the highest level. His players backed him up with an impressive counter-attacking performance. Games against Chelsea and Manchester United are up next.Share this:FacebookRedditTwitterPrintPinterestEmailWhatsAppSkypeLinkedInTumblrPocketTelegramlast_img read more

Morning Reaction Picks and Comment – Week 10

first_imgHere are this weekend’s picks as Drew Forrester and Luke Jones will pick every NFL game as well as local college football contests.Drew Forrester is 87-44 after finishing 9-5 last week while Luke Jones is 87-44 after a 9-5 record in Week 9. Both are 0-1 this week after incorrectly picking San Diego to defeat Oakland on Thursday night (the loss is already included in the aforementioned records). Official standings are only kept based on the NFL picks.Ravens at Seahawks: Baltimore 34-10 (Drew), Baltimore 23-13 (Luke)Steelers at Bengals: Cincinnati 20-17 (Drew), Pittsburgh 20-14 (Luke)Broncos at Chiefs: Kansas City 28-19 (Drew), Kansas City 24-20 (Luke)Jaguars at Colts: Indianapolis 13-9 (Drew), Indianapolis 13-10 (Luke)Bills at Cowboys: Buffalo 27-20 (Drew), Dallas 23-20 (Luke)Texans at Buccaneers: Tampa Bay 24-20 (Drew), Houston 24-23 (Luke)Titans at Panthers: Carolina 24-17 (Drew), Carolina 21-16 (Luke)Redskins at Dolphins: Miami 17-16 (Drew), Miami 17-13 (Luke)Saints at Falcons: New Orleans 27-24 (Drew), New Orleans 27-21 (Luke)Lions at Bears: Chicago 27-20 (Drew), Chicago 20-17 (Luke)Rams at Browns: Cleveland 17-10 (Drew), Cleveland 16-10 (Luke)Cardinals at Eagles: Philadelphia 37-7 (Drew), Philadelphia 27-13 (Luke)Giants at 49ers: New York 24-21 OT (Drew), San Francisco 24-17 (Luke)Patriots at Jets: New England 28-24 (Drew), New England 25-20 (Luke)Vikings at Packers: Green Bay 36-24 (Drew), Green Bay 31-17 (Luke)Maryland at Notre Dame: Fighting Irish 34-20 (Drew), Fighting Irish 27-14 (Luke)New Hampshire at Towson: Tigers 26-23 (Drew), Tigers 24-17 (Luke)Navy at SMU: Mustangs 30-20 (Drew), Mustangs 21-14 (Luke)Norfolk State at Morgan State: Spartans 35-10 (Drew), Spartans 24-20 (Luke)last_img read more

Yusuf Mannan pays ode to Burma teak

first_imgMannan’s line of library furniture looks like colourful waves on the wallAllium sativum, better known as garlic, is a mundane kitchen essential. But Bangladesh-based designer Yusuf Mannan has put a new spin on the staple with his Lehsoon range of lamps, which mirror the shape of their namesake. The lampshades,,Mannan’s line of library furniture looks like colourful waves on the wallAllium sativum, better known as garlic, is a mundane kitchen essential. But Bangladesh-based designer Yusuf Mannan has put a new spin on the staple with his Lehsoon range of lamps, which mirror the shape of their namesake. The lampshades, fashioned out of translucent fabric, mimic the delicate garlic casing while the pedestal is a roughly-hewn piece of teak wood.The Lehsoon lamps are fashioned from fabric and teakThe National Institute of Design (NID) graduate’s other muses are equally eclectic. He claims to be inspired by the Shakers, an 18th century religious group founded in England, local Gujarati artisans called kakas and even charming doll’s houses. Inevitably, this 33-year-old’s creations reflect his varied influences while celebrating individuality and technique.Mannan believes that beauty and functionality go hand in hand. As a result, his line of furniture and lifestyle products bear the unmistakable stamp of originality while addressing practical concerns. The designer’s miniature collection is made out of salvaged scraps of woodThough imaginative, the young designer likes to steer clear of over-the-top ornamentation. Instead, he loves to play around with natural textures and shapes while crafting his products.At his Dhaka studio, you can browse through the Mangrove Collection which sings paeans to untreated wood. The series is noted for its spartan chairs, tables and recliners with grainy, unpolished surfaces. “I am mostly inspired by the natural world. When in doubt, I try and draw parallels from nature to come up with a solution,” he says by way of explanation.Despite possessing a bare-bones aesthetic, all his furniture pieces exude personality. And yes, his designs are a far cry from heavily-embellished items that populate most urban living spaces. “A lot of my recent creations take inspiration from Shaker furniture that rarely sported elaborate details,” says the maverick.Over his decade long career, Mannan has worked with sundry materials but it is wood that ticks all his design checkboxes. “My first and only love is wood, Burma teak to be more specific. It has beautiful grains, the sweetest fragrance and is very forgiving too,” he explains.Reconfiguring familiar shapes is Mannan’s forte. So his Library Collection has curved racks in vibrant tones instead of conventional straight-lined shelves. Cocking a snook at tradition, the designer has also come up with a miniature line of furniture with thumb-sized beds, tables and dressers that are just right for a doll’s house. “I salvaged scraps of wood and set out to make miniatures. At that scale you really begin to understand the material better and when you revert to actual scale, you start being more precise,” he elaborates on his style, adding that his next step would be to make entire dollhouses, down to the last little detail.The Time Tree installation, made for Wipro, combines wires and clocksNo stranger to the world of unorthodox shapes and proportions, Mannan has a unique way of functioning. He barely sketches on paper anymore. When an idea strikes, he rushes to his workshop, starts drawing on a piece of wood and eventually executes the design. All his creations are handcrafted and retailed through his website.But this avant-garde designer, who employs traditional wood-crafting techniques in new ways, also has a knack for fashioning thematic interiors. He started a firm called Bent by Design in 2007 with Hidish Salam, a furniture designer from Srishti School of Art, Design and Technology, and T.When an idea strikes Mannan, he executes the design without drawing on paperKuldeep, another alumnus from NID. Since then, the trio has worked on different platforms of design. But the jewel in the label’s crown is the futuristic experiential space in the Wipro campus, Bangalore. From an installation made out of clocks and colourful cables titled Time Tree to lines replicating race tracks, the space is built around a Formula 1 theme.”The F1 pit stop has been used as a metaphor for speedy customer service,” explains the designer.Just like the sport, design, according to Mannan, is synonymous with play. But it is serious play, and he definitely wants to stay ahead of the pack.advertisementlast_img read more

a month ago​Brighton midfielder Stephens: I’ve never played in a team like this

first_img​Brighton midfielder Stephens: I’ve never played in a team like thisby Ansser Sadiqa month agoSend to a friendShare the loveBrighton midfielder Dale Stephens admits that he has never played on a team with such quality.The Albion have gone through a change in style this summer, with manager Graham Potter favouring a possession based, attacking game plan.And Stephens admits that having so much of the ball in games is a change for him, given the way his teams have usually played throughout his career.Asked by reporters if he has played in such a team before, Stephens responded by saying:”No, honestly not.”It’s the first time I have played in a system that probably suits me better, I would say.”It probably suits the players and individuals we have at the club at the minute.”Everyone is enjoying playing in a team that is dominating possession.” About the authorAnsser SadiqShare the loveHave your saylast_img read more

Tiger Woods Never Really Left

The injuries and the extended absences gave Tiger ample time to fade into the background while a crop of young stars like McIlroy and Spieth ascended. But Tiger never really went away: Even though he hasn’t spent much time on the golf course, he still managed to garner more headlines than the others in this group in 24 of the past 47 months.The months since 2014 in which Tiger’s mentions are surpassed by any of these players mostly track with a given player’s success — or a given player’s epic collapse — at a major championship. For example, McIlroy’s headline mentions outpaced Tiger’s in July 2014 when he finally got over the hump to win his first British Open. Spieth’s mentions exceeded Tiger’s in June 2015 when he became the first 21-year-old to win the U.S. Open since Bobby Jones did so in 1923. In August 2015, Day and Spieth battled for the PGA Championship (where McIlroy was the defending champion). Day ultimately edged Spieth to claim the Wanamaker Trophy, and all three players’ names popped up in the media more frequently than Tiger’s that month.And even if Tiger had been swinging his sticks in April 2016 — he effectively disappeared from the public eye for much of that year — it’s safe to assume Spieth would have still topped Tiger that month: Spieth’s quadruple-bogey at Amen Corner on Sunday at the Masters was the story of the golf season, if not golf’s past half-decade.Tiger’s mentions spiked again in October 2016 when rumors of his return to competitive golf began to swirl (though he eventually postponed that return), and he’s remained steadily at or around the top since.4One big exception: July 2017, when Spieth and McIlroy battled for the Claret Jug at Royal Birkdale. And Tiger’s biggest peak came in late May and early June of this year after his arrest on suspicion of driving under the influence of, well, seemingly everything.5We’ve all seen the mugshot; we don’t need to make another joke about the mugshot.The overall trend has held true over the past two years, even as Tiger has been nonexistent in professional golf. Here’s how Woods has compared over that span to the top 10 PGA Tour money leaders in headlines,6Doesn’t include money earned on the European Tour and other non-PGA Tour circuits. according to Media Cloud. The 18-man field of this week’s Hero World Challenge1This event is hosted by Tiger Woods and is a benefit for the Tiger Woods Foundation. — a tournament that seems to function mostly as an excuse to wrangle the world’s best golfers and Derek Jeter for a hang in the Bahamas — features eight players ranked in the top 10 and nine others ranked no lower than No. 32. Rounding out the field is the world’s 1,199th-ranked golfer, otherwise known as Tiger Woods. Take a guess at who’s getting the lion’s share of attention?Woods made his latest return to professional golf on Thursday, giving us another excuse to indulge in a long-running national obsession. Tiger hasn’t won a tournament since 2013, and he hasn’t made a cut since 2015. He played just four meaningful2Assuming you count last year’s Hero World Challenge as “meaningful.” rounds of golf in 2016, and the event in the Bahamas is his first start in 10 months.But Woods’s prolonged absence hasn’t sidelined his status as golf’s biggest celebrity. To measure this using the Media Cloud — a database that collects news published on the internet every day — we looked at every time the words “Tiger Woods” appeared in a headline on a mainstream U.S. media outlet from the beginning of 2014 to the eve of the Hero World Challenge. Tiger garnered 4,489 articles3This may include different versions of the same story. despite making just 22 starts in that time. This number exceeds each of the five players who have held the No. 1 world ranking since Woods last gave it up: Rory McIlroy (3,844 headlines), Jordan Spieth (2,682), Dustin Johnson (1,207), Jason Day (995) and Adam Scott (512). The irony here is that these past two years have been an exciting time for golf as numerous stars have emerged in the Tigerless landscape. Over the course of the past two PGA Tour seasons, the 10 players in the chart above — which includes exciting American talents such as Justin Thomas, Rickie Fowler and Patrick Reed — have combined to rack up more than $100 million and win four of the past eight majors. Despite the cupboard being stocked with all the ingredients for a piquant tabloid stew — youth, success, money, celebrity relationships, some casual cocaine use — none of these moneyed young players in the primes of their careers have managed to grow their personal brand enough to surpass the ultimate golf celebrity.Tiger Mania has had peaks and valleys, but it’s never died down entirely. If Tiger says his back is feeling good, we’re paying attention. If Tiger sneezes, we’re paying attention. And if Tiger messes up, we’re definitely paying attention. But now that he’s picked up the bag again, it would be nice if the quality of his game returned to the sublime golf that made us fall in love with him to begin with — and allow us to focus on that.Geoff Foster contributed research to this piece. read more

Star power on and off the court propel Ohio State to win

As you’d expect for a game as highly anticipated as the one between Ohio State and Duke, half of the pre-game entrances were filled with cheers and the other half were filled with boos. But on Tuesday night, those cheers didn’t initially come for Thad Matta and his Buckeyes, nor did the boos first come for Mike Krzyzewski and the Blue Devils. Instead it was former OSU players Evan Turner, Mike Conley, Jr., Greg Oden, Michael Redd and Scoonie Penn receiving cheers as they arrived to their courtside seats, moments before the Miami Heat’s Dwyane Wade and LeBron James received a chorus of boos on the way to theirs. But with the stars of the NBA and OSU’s past lining the north baseline, the real stars Tuesday night were in uniform, as anyone who was looking forward to stat-sheet-stuffing individual performances from the No. 2- and No. 3-ranked teams in the nation didn’t walk away from the Schottenstein Center disappointed. OSU’s trio of preseason National Player of the Year candidates combined for 58 points as the Buckeyes cruised to a 85-63 win. Totals in the OSU box score included 21 points and eight rebounds from preseason All-American Jared Sullinger, 20 points, five rebounds and four assists from William Buford, and 17 points, eight assists and five rebounds from sophomore guard Aaron Craft. After the game, Sullinger attributed the Buckeyes’ domination against Duke to the team’s mental toughness. “What can I say? This basketball team is something special,” Sullinger said. “We really kind of took them by their throats, and we really kind of pushed the ball, and we got a lot of easy baskets.” Despite their large margin of victory, it wasn’t just the Buckeyes’ stars who put on a show. Highly touted Duke freshman guard Austin Rivers had a coming out party of sorts, as he led the Blue Devils in scoring with 22 points — two of which came by way of an ankle-breaking crossover and then lay-up as he was guarded by OSU’s Jordan Sibert. Also starring for Duke was junior forward Mason Plumlee — a former McDonald’s All-American and 2009’s Mr. Basketball in North Carolina — who scored 16 points and added six rebounds for the Blue Devils on Tuesday night. “Those two kids were excellent for us,” Krzyzewski said. “They’re going to get better. Our team is going to get a lot better by playing this level of competition.” The efforts of Rivers and Plumlee weren’t enough, however, as not only did Duke have to deal with the star power of Sullinger, Buford and Craft, but that of an emerging star in OSU sophomore Deshaun Thomas. Also a former high school All-American, Thomas scored a season-high 18 points, including a buzzer beating jumper at the end of the first half to give the Buckeyes a 47-28 lead at intermission. After the game, Thomas admitted that James’ and Wade’s presence played a role in inspiring him for his big game on the big stage. “I saw them over there. They’re guys you watch in the NBA every day,” Thomas said. “It was great motivation to show off for them, ‘cause they show off for us when they’re on the TV.” But while he looked like an NBA player Tuesday night, unlike James and Wade, Thomas’ star power was anything but booed by the sold out crowd of 18,809 at the Schottenstein Center. read more